The Response of Hematological Factors to Home-Based Exercise Rehabilitation and Center-Based Cardiac Rehabilitation in Coronary Artery Disease

Background: Hematological disorders such as increased white blood cells and platelets (elevated white blood cell and platelets) in coronary heart disease (CHD) are associated with increased mortality. Exercise could specifically influence hematologic factors. The purpose of this study was to survey the response of hematological factors to home-based exercise rehabilitation and center-based cardiac rehabilitation in coronary artery disease. Methods: This semi-experimental study was conducted on 40 patients (mean age, 59 ± 6.28 years) in Isfahan cardiovascular research center. The participants were voluntarily divided into 3 groups: home-based exercise rehabilitation (n=13), centre-based CR(n=15) and control(n=12). white blood cell (WBC), red blood cell (RBC), hemoglobin (Hb), hematocrit (Hct), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular volume (MCV) and Platelets (PLT) were measured at baseline and after 2 months of CR. Data were analyzed using analysis of one- way ANOVA in P<0.05 level.   Results: After 2 months of CR, MCH and MCHC in the home-based exercise rehabilitation group and Hb, Hct and MCV in the centre-based CR group increased significantly. In home-based exercise rehabilitation group, RBC, PLT and Hb associated with a significant decrease. Conclusion: the regular, moderate- intensity physical activity in both groups of cardiac rehabilitation led to relatively improvement some of the hematological factors.